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Optogenetics is a biological technique which involves the use of light to control cells in living tissue, typically neurons, that have been genetically modified to express light-sensitive ion channels. It is a neuromodulation method that uses a combination of techniques from optics and geneticsto control and monitor the activities of individual neurons in living tissue—even within freely-moving animals—and to precisely measure these manipulation effects in real-time
In 2010, optogenetics was chosen as the “Method of the Year” across all fields of science and engineering by the interdisciplinary research journal Nature Methods.At the same time, optogenetics was highlighted in the article on “Breakthroughs of the Decade” in the academic research journal Science. These journals also referenced recent public-access general-interest video Method of the year video and textual SciAm summaries of optogenetics.
An innovative technique for generating a three-dimensional holographic display using strontium barium niobate (SBN) is discussed. The resultant image is a hologram that can be viewed in real time over a wide perspective or field of view (FOV). The holographic image is free from system-induced aberrations and has a uniform, high quality over the entire FOV. The enhanced image quality results from using a phase-conjugate read beam generated from a second photorefractive crystal acting as a double-pumped phase-conjugate mirror (DPPCM). Multiple three-dimensional images have been stored in the crystal via wavelength multiplexing.
Researchers at Harvard University have created a brain-to-brain interface (BBI) between a human and a Sprague-Dawley rat. Simply by thinking the appropriate thought, the BBI allows the human to control the rat’s tail. The human wears an EEG-based brain-to-computer interface (BCI), while the anesthetised rat is equipped with a focused ultrasound (FUS) computer-to-brain interface (CBI). FUS is a technology that allows the researchers to excite a specific region of neurons in the rat’s brain using an ultrasound signal (350 kHz ultrasound frequency, tone burst duration of 0.5 ms, pulse repetition frequency of 1 kHz, given for 300 ms duration). The main advantage of FUS is that, unlike most brain-stimulation techniques, it is non-invasive. Whenever the human looks at a specific pattern (strobe light flicker) on a computer screen, the BCI communicates a command to the rat’s CBI, which causes ultrasound to be beamed into the region of the rat’s motor cortex responsible for tail movement. The researchers report that the human BCI has an accuracy of 94%, and that it generally takes around 1.5 s from the human looking at the screen to movement of the rat’s tail
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